In loco retention effect of magnetic core mesoporous silica nanoparticles doped with trastuzumab as intralesional nanodrug for breast cancer
نویسندگان
چکیده
منابع مشابه
Mesoporous Silica Nanoparticles as Drug Delivery Vehicles in Cancer
Even though cancer treatment has improved over the recent decades, still more specific and effective treatment concepts are mandatory. Surgical removal is not always possible, metastases are challenging and chemo- and radiotherapy can not only have severe side-effects but also resistances may occur. To cope with these challenges more efficient therapies with fewer side-effects are required. One...
متن کاملThe Effects of Morphology on Mesoporous Silica Nanoparticles as a Targeted Theranostic for Breast Cancer
777 ©2014 Society for Biomaterials
متن کاملThe effect of mesoporous silica nanoparticles loaded with epirubicin on drug-resistant cancer cells
Objective (s): In chemotherapy for cancer treatment, the cell resistance to multiple anticancer drugs is the major clinical problem. In the present study, mesoporous silica nanoparticles (MSNs) were used as a carrier for epirubicin (EPI) in order to improve the cytotoxic efficacy of this drug against the P-glycoprotein (P-gp) overexpressing cell line. Materials and Methods: MSNs with phosphonat...
متن کاملFacile and Economic Method for the Preparation of Core-Shell Magnetic Mesoporous Silica
In this work core-shell structure Fe3O4@SiO2@meso-SiO2 microsphere has been successfully prepared. An inorganic magnetic core has been coated with multi-shell structure, dense nonporous silica as an inner layer and mesoporous silica as an outer layer. The dense silica shell can enhance the stability and minimize the negative effect of acidic condi...
متن کاملAn Investigation on Synthesis and Magnetic Properties of Manganese Doped Cobalt Ferrite Silica Core-Shell Nanoparticles for Possible Biological Application
In this work, we investigated synthesis, magnetic properties of silica coated metal ferrite, (CoFe2O4)/SiO2 and Manganese doped cobalt ferrite nanoparticles (MnxCo1-xFe2O4 with x= 0.02, 0.04 and 0.06)/SiO2 for possible biomedical application. All the ferrites nanoparticles were prepared by co-precipitation method using FeCl3.6H2O, CoCl2.6H2O and MnCl2.2H2O as precursors, and were silica coated ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Artificial Cells, Nanomedicine, and Biotechnology
سال: 2018
ISSN: 2169-1401,2169-141X
DOI: 10.1080/21691401.2018.1508030